L-Citrulline
An amino acid included in many pre-workout formulas.
Last reviewed 19 Sept 2026
What is it?
L-citrulline is an amino acid that contributes to nitric oxide production.
Why is it used?
Included in pre-workout formulas marketed to support blood flow and 'pump'.
How does it work?
It supports nitric oxide production, which is involved in blood vessel function.
Common uses
- Pre-workout formulas
- Pump-focused products
What does research suggest?
Research suggests it may support aspects of blood flow during exercise; effects vary.
Potential benefits
- May support blood flow during exercise
- Commonly studied
Limitations
- Effects vary
- Not necessary for all training
- Dose-dependent
Safety considerations
Generally well tolerated. Consult a healthcare professional if unsure.
Who should be cautious?
- Those on blood-pressure medication
- Anyone unsure about suitability
Common supplement forms
- L-citrulline
- Citrulline malate
Frequently asked questions
Is citrulline the same as arginine?
No, but they relate to the same pathway; citrulline is often used for absorption reasons.
Medical Disclaimer
This content is for general educational purposes only and is not personalised medical advice. Always consult a qualified healthcare professional before making changes to your diet, training or supplement use.